Ameliorative effect of Koflet formulations against pyridine-induced pharyngitis in rats

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Ameliorative effect of Koflet formulations against pyridine-induced pharyngitis in rats

In present study two formulations of Koflet (syrup and lozenges) were evaluated against pyridine-induced pharyngitis in rats. Topical application of 10% pyridine showed extravasation of Evans blue stain as a characteristic feature of on-going inflammation. In addition, the levels of TNF-α (p < 0.01) and IL-6 (p < 0.01) were significantly increased compared to control. Further, histopathology of...

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ژورنال

عنوان ژورنال: Toxicology Reports

سال: 2014

ISSN: 2214-7500

DOI: 10.1016/j.toxrep.2014.05.003